发明名称 EXPRESSION VECTORS BASED ON MODIFIED RIBOSOMAL PROTEIN PROMOTERS AND USES THEREOF IN POST-TRANSCRIPTIONAL ASSESSMENT
摘要 <p>The present invention relates to expression vector comprising (a) a promoter region comprising a non-inducible constitutively active ribosomal protein gene promoter, (b) an operably linked reporter or gene sequence, and (c) a 3' untranslated region (3' UTR), which are suitable means for an selective assessment of post-transcriptional regulation, post-transcriptional con-trol elements and factors as well as for identifying compounds that effect post-transcription. The present invention furthermore re-lates to arrays, expression vector libraries and cell lines containing the expression vector(s). The present invention furthermore re-lates to a method and kit for identifying compounds that affect post-transcriptional regulation of reporter(s) or gene(s), that utilize the expression vector(s).</p>
申请公布号 CA2729254(C) 申请公布日期 2015.02.24
申请号 CA20082729254 申请日期 2008.11.17
申请人 KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER 发明人 KHABAR, KHALID S. ABU
分类号 C12Q1/68;C12N15/79 主分类号 C12Q1/68
代理机构 代理人
主权项
地址