Dry composition wound dressings and adhesives comprising gelatin and transglutaminase in a cross-linked matrix

摘要

Patches comprising dry gelatin compositions.

主权项

1. A patch comprising an implantable surgical mesh, a cross-linkable protein matrix and a protein cross-linking enzyme in contact with said matrix for cross-linking said cross-linkable protein, wherein said matrix is incorporated into, layered on or surrounding said mesh, with the proviso that said enzyme is not thrombin, wherein said cross-linkable protein comprises gelatin, wherein said gelatin is present in a protein matrix and wherein said matrix has a density in a range of from 5 to 100 mg/cm3, wherein said cross-linkable protein matrix comprises porous gelatin foam.