发明名称 Linezolid intermediate and method for synthesizing linezolid
摘要 Provided are a linezolid intermediate and the preparation method thereof and a method for synthesizing linezolid. The structure of the intermediate is shown as formula F2, wherein the compound is prepared by a condensation reaction of (S)—N-(3-chloro-2-hydroxy-1-propyl) acetamide and the compound shown in formula F4. In the preparation methods of the compound shown in formula F2 and linezolid, the reaction system is mild, side reactions are few and the product yield is high.;
申请公布号 US8962827(B2) 申请公布日期 2015.02.24
申请号 US201214008124 申请日期 2012.04.12
申请人 Zhejiang Medicine Co. Ltd. Xinchang Pharmaceutical Factory 发明人 Jiang Xiaoyue;Wu Guofeng;Ye Weidong;Shen Runpu;Song Xiaohua
分类号 C07D413/10;C07C233/18;C07D263/20;C07C231/12;C07D263/24 主分类号 C07D413/10
代理机构 Ballard Spahr LLP 代理人 Ballard Spahr LLP
主权项 1. A compound of formula F2,wherein R is hydrocarbon group.
地址 Chengguan Town, Xinchang CN