发明名称 Transdermal therapeutic system for administering rivastigmine or derivatives thereof
摘要 The present invention relates to a transdermal therapeutic system for administering an active substance through the skin, comprising: a) a cover layer,b) a reservoir present on the cover layer, comprising a polymer matrix comprising the active substance,c) an adhesive layer present on the reservoir comprising a contact adhesive, andd) a removable layer present on the adhesive layer, the active substance being rivastigmine, a physiologically compatible salt, hydrate, solvate or derivative thereof, characterized in that the polymer matrix of the reservoir comprises neither hydroxyl groups nor carboxyl groups.
申请公布号 US8962014(B2) 申请公布日期 2015.02.24
申请号 US201013518006 申请日期 2010.12.14
申请人 Acino AG 发明人 Prinz Heike;Schurad Björn;Beckert Thomas;Linder Kristina
分类号 A61F13/00;A61K9/70;A61K31/27 主分类号 A61F13/00
代理机构 Curatolo Sidoti Co., LPA 代理人 Curatolo Sidoti Co., LPA ;Curatolo Joseph G.;Sidoti Salvatore A.
主权项 1. A transdermal therapeutic system for administering an active substance through the skin comprising: a) a cover layer, b) a reservoir present on the cover layer, comprising a polymer matrix, c) an adhesive layer on the reservoir comprising a contact adhesive, and d) a removable layer present on the adhesive layer,wherein the active substance is rivastigmine or a physiologically tolerable salt, hydrate, solvate or derivative thereof, andwherein the polymer matrix of the reservoir includes neither hydroxyl groups nor carboxyl groups.
地址 Miesbach DE