发明名称 |
Transdermal therapeutic system for administering rivastigmine or derivatives thereof |
摘要 |
The present invention relates to a transdermal therapeutic system for administering an active substance through the skin, comprising:
a) a cover layer,b) a reservoir present on the cover layer, comprising a polymer matrix comprising the active substance,c) an adhesive layer present on the reservoir comprising a contact adhesive, andd) a removable layer present on the adhesive layer,
the active substance being rivastigmine, a physiologically compatible salt, hydrate, solvate or derivative thereof,
characterized in that the polymer matrix of the reservoir comprises neither hydroxyl groups nor carboxyl groups. |
申请公布号 |
US8962014(B2) |
申请公布日期 |
2015.02.24 |
申请号 |
US201013518006 |
申请日期 |
2010.12.14 |
申请人 |
Acino AG |
发明人 |
Prinz Heike;Schurad Björn;Beckert Thomas;Linder Kristina |
分类号 |
A61F13/00;A61K9/70;A61K31/27 |
主分类号 |
A61F13/00 |
代理机构 |
Curatolo Sidoti Co., LPA |
代理人 |
Curatolo Sidoti Co., LPA ;Curatolo Joseph G.;Sidoti Salvatore A. |
主权项 |
1. A transdermal therapeutic system for administering an active substance through the skin comprising:
a) a cover layer, b) a reservoir present on the cover layer, comprising a polymer matrix, c) an adhesive layer on the reservoir comprising a contact adhesive, and d) a removable layer present on the adhesive layer,wherein the active substance is rivastigmine or a physiologically tolerable salt, hydrate, solvate or derivative thereof, andwherein the polymer matrix of the reservoir includes neither hydroxyl groups nor carboxyl groups. |
地址 |
Miesbach DE |