发明名称 Method of treating retinitis pigmentosa
摘要 Provided is a method for improving day photopic vision and/or cone-derived visual field and visual function in a subject suffering from a retinal disease or trauma including administering to the subject a pharmaceutically effective amount of crude Dunaliella powder. Also provided is a method for improving night vision and/or rod derived visual field in a subject suffering from a retinal disease including administering to the subject a pharmaceutically effective amount of crude Dunaliella powder. A pharmaceutical composition for improving day vision and/or visual field in a subject suffering from a retinal disease including crude Dunaliella powder is also provided.
申请公布号 US8961993(B2) 申请公布日期 2015.02.24
申请号 US201313945366 申请日期 2013.07.18
申请人 Nikken Sohonsha Corporation;Tel Hashomer Medical Research Infrastructure and Services Ltd. 发明人 Belkin Michael;Shaish Aviv;Harats Dror;Rotenstreich Ygal
分类号 A61K36/05 主分类号 A61K36/05
代理机构 Vorys, Sater, Seymour and Pease LLP 代理人 Vorys, Sater, Seymour and Pease LLP ;Hopkins Susanne M.
主权项 1. A method for improving night vision and/or rod derived visual field and visual function in a subject suffering from a retinal disease, comprising: administering to a subject in need thereof a pharmaceutically effective amount of a capsule dosage form comprising crude Dunaliella powder that is filled in a capsule under normal atmosphere to produce the capsule dosage form, the crude Dunaliella powder comprising β-carotene at an approximately 1:1 ratio of 9-cis and all-trans β-carotene isomers, or a greater than 1:1 ratio of 9-cis and all-trans β-carotene isomers.
地址 Hashima, Gifu JP