发明名称 |
Method of treating retinitis pigmentosa |
摘要 |
Provided is a method for improving day photopic vision and/or cone-derived visual field and visual function in a subject suffering from a retinal disease or trauma including administering to the subject a pharmaceutically effective amount of crude Dunaliella powder. Also provided is a method for improving night vision and/or rod derived visual field in a subject suffering from a retinal disease including administering to the subject a pharmaceutically effective amount of crude Dunaliella powder. A pharmaceutical composition for improving day vision and/or visual field in a subject suffering from a retinal disease including crude Dunaliella powder is also provided. |
申请公布号 |
US8961993(B2) |
申请公布日期 |
2015.02.24 |
申请号 |
US201313945366 |
申请日期 |
2013.07.18 |
申请人 |
Nikken Sohonsha Corporation;Tel Hashomer Medical Research Infrastructure and Services Ltd. |
发明人 |
Belkin Michael;Shaish Aviv;Harats Dror;Rotenstreich Ygal |
分类号 |
A61K36/05 |
主分类号 |
A61K36/05 |
代理机构 |
Vorys, Sater, Seymour and Pease LLP |
代理人 |
Vorys, Sater, Seymour and Pease LLP ;Hopkins Susanne M. |
主权项 |
1. A method for improving night vision and/or rod derived visual field and visual function in a subject suffering from a retinal disease, comprising:
administering to a subject in need thereof a pharmaceutically effective amount of a capsule dosage form comprising crude Dunaliella powder that is filled in a capsule under normal atmosphere to produce the capsule dosage form, the crude Dunaliella powder comprising β-carotene at an approximately 1:1 ratio of 9-cis and all-trans β-carotene isomers, or a greater than 1:1 ratio of 9-cis and all-trans β-carotene isomers. |
地址 |
Hashima, Gifu JP |