| 发明名称 |
N-(2-(HETARIL)ARIL)ARILSULFONAMIDAS E N-(2-(HETARIL)ARILSULFONAMIDAS |
| 摘要 |
Compounds are provided that act as potent antagonists of the CCR9 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR9-mediated diseases, and as controls in assays for the identification of CCR9 antagonists. |
| 申请公布号 |
BRPI0814719(A2) |
申请公布日期 |
2015.02.24 |
| 申请号 |
BR2008PI14719 |
申请日期 |
2008.06.18 |
| 申请人 |
CHEMOCENTRYX, INC. |
发明人 |
CHENG HU;ANITA MELIKIAN;AARON NOVACK;ANDREW M.K. PENNELL;JAY POWERS;SREENIVAS PUNNA;EDWARD J. SULLIVAN;WILLIAM D. THOMAS;SOLOMON UNGASHE;PENGLIE ZHANG;TREVOR T. CHARVAT |
| 分类号 |
C07D209/08;C07D231/12;C07D231/14;C07D231/16;C07D231/56;C07D233/61;C07D235/08;C07D249/06;C07D249/18;C07D401/04;C07D401/14;C07D413/04;C07D413/14;C07D417/04;C07D471/04 |
主分类号 |
C07D209/08 |
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