Method of using a fiber matrix for maintaining space in soft tissues

摘要

A fiber matrix is provided for maintaining space in soft tissue, for example for use in procedures for assisting drainage of aqueous humor from an eye to treat glaucoma. The fiber matrix comprises a plurality of crossing fibers forming a mesh with a plurality of void spaces. The fibers and void spaces are sized and arranged so as to permit passage of fluid through the fiber matrix and to inhibit formation of scar tissue through the fiber matrix. The fibers may comprise a polymeric material, and the fiber matrix may be manufactured by electrospinning. The fibers may comprise a biostable and/or a biodegradable material. In one method of using a fiber matrix, the fiber matrix is positioned under a scleral flap, with at least part of the fiber matrix under the scleral flap.

主权项

1. A method of using a fiber matrix in treatment of glaucoma comprising:
(i) performing a procedure for increasing the flow of aqueous humor from an eye, the procedure including creating a scleral flap; (ii) lifting the scleral flap to allow access to a scleral well beneath the scleral flap; (iii) positioning a fiber matrix such that a first part of the fiber matrix is located in the scleral well and a second part of the fiber matrix is located outside of the scleral well, wherein the fiber matrix comprises a plurality of crossing fibers forming a mesh with a plurality of void spaces; and (iv) replacing the scleral flap such that the first part of the fiber matrix is implanted under the scleral flap and the second part of the fiber matrix is implanted outside of the scleral flap and on top of the sclera; wherein the fiber matrix, by the size and arrangement of the fibers and void spaces of the fiber matrix, permits passage of aqueous humor through the fiber matrix and inhibits formation of scar tissue through the fiber matrix.