发明名称 Alloplastic injectable dermal filler and methods of use thereof
摘要 A composition comprising an alloplastic injectable suspension for use as a dermal filler comprising a biocompatible and pliable material and a physiologically acceptable suspending agent is provided. A method of making a composition comprising an alloplastic injectable suspension for use as a dermal filler comprising a biocompatible and pliable material and a physiologically acceptable suspending agent, said method comprising admixing a biocompatible and pliable material with a physiologically acceptable suspending agent, is also provided. A method of augmenting soft tissue to provide long-term reduction of a skin defect, said method comprising stimulating collagen beneath the skin defect is further provided. In an embodiment of the method of augmenting soft tissue, the stimulation of collagen production is effected by injecting into the deep reticular dermis an a dermal filler, said dermal filler being an alloplastic injectable suspension and comprising a biocompatible and pliable material and a physiologically acceptable suspending agent.
申请公布号 US8962002(B2) 申请公布日期 2015.02.24
申请号 US201313740836 申请日期 2013.01.14
申请人 发明人 Boutros Ayman
分类号 A61K31/78;A61K47/32;A61K8/65;A61K8/81;A61K9/10;A61Q19/08;A61L27/16;A61L27/26;A61K8/02;A61K8/73;A61K9/00;A61K9/16;A61K47/36;A61K47/42;A61K31/785 主分类号 A61K31/78
代理机构 Hunton & Williams LLP 代理人 Hunton & Williams LLP
主权项 1. A method for reducing wrinkles or scars comprising injecting a dermal filler below the skin at a junction of the dermis and subcutaneous fat, wherein said dermal filler comprises a biocompatible and pliable material and a physiologically acceptable suspending agent, wherein said biocompatible and pliable material is a copolymer of an unsubstituted acrylate monomer and a substituted acrylate monomer, wherein the biocompatible and pliable material comprises particles having a diameter of less than about 100 μ.
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