| 发明名称 | Nanoparticles for delivery of active agents | ||
| 摘要 | Milled nanoparticles comprising a biologically active agent, at least one biopolymer and a coating containing at least one coating which is a polymer or ligand are produced using milling and coating techniques which have not previously been used for these applications. | ||
| 申请公布号 | US8962030(B2) | 申请公布日期 | 2015.02.24 |
| 申请号 | US201012943566 | 申请日期 | 2010.11.10 |
| 申请人 | Jyant Technologies, Inc. | 发明人 | Lillard James W.;Singh Rajesh;Singh Shailesh |
| 分类号 | A61K9/16;A61K31/337;A61K9/14;A61K9/51;A61K33/24;A61K47/48;A61K9/50;A61K38/00 | 主分类号 | A61K9/16 |
| 代理机构 | Andrews Kurth LLP | 代理人 | Wang Ping;Andrews Kurth LLP |
| 主权项 | 1. A method for treating cancer in a subject, comprising: administering to the subject, an effective amount of a pharmaceutical composition comprising a planetary ball milled particle comprising: an anti-cancer agent;polyethylene glycol;polycaprolactone, anda biopolymer selected from the group consisting of starch, cellulose, collagen, lactose and alginate,wherein the planetary ball milled particle is coated with polycaprolactone and has a size in the range of 5 nm to 50 μm. | ||
| 地址 | Marietta GA US | ||