发明名称 TAXANE-CONTAINING AMPHIPHILIC BLOCK COPOLYMER MICELLE COMPOSITION AND MANUFACTURING METHOD OF THE SAME
摘要 PROBLEM TO BE SOLVED: To provide a taxane-containing amphiphilic block copolymer micelle composition having improved stability, in an effort to solve the above-described problems associated with the related art.SOLUTION: A taxane-containing amphiphilic block copolymer micelle composition includes taxane, an amphiphilic block copolymer containing a hydrophilic block and a hydrophobic block, and an osmolality adjusting agent. Also described is a method for preparing the same composition. The composition has excellent stability, so that it can prevent rapid release of a drug and can improve a pharmacological effect. Additionally, the method enables highly efficient preparation of the composition.
申请公布号 JP2015034172(A) 申请公布日期 2015.02.19
申请号 JP20140224575 申请日期 2014.11.04
申请人 SAMYANG BIOPHARMACEUTICALS CORP 发明人 LEE SA-WON;SEO MIN-HYO
分类号 A61K9/51;A61K31/337;A61K45/00;A61K47/02;A61K47/26;A61K47/34;C08J3/07;C08J3/14;C08K5/053;C08K5/16;C08L67/04;C08L71/02 主分类号 A61K9/51
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