发明名称 NEW HYDROXYSAFFLOR YELLOW PHARMACEUTICAL SALTS
摘要 Provided are new hydroxysafflor yellow A pharmaceutical salts as presented in formula (I), in particular new monomer compounds of potassium, ammonium, calcium, and magnesium salts of hydroxysafflor yellow A, preparation method therefor, and medical uses thereof. Compared to hydroxysafflor yellow A, the hydroxysafflor yellow A pharmaceutical salts of the present invention have a purity of at least 98% and are monomer compounds that are safer, more effective, stable, and controllable. The salts have the effects against PAF- or ADP-induced platelet aggregation, and can be used in treating blood circulatory disorders such as platelet aggregation, coronary artery diseases, angina, and acute cerebral ischemia to the effect comparable to hydroxysafflor yellow A. M and n are defined as in the description.
申请公布号 WO2014121666(A8) 申请公布日期 2015.02.19
申请号 WO2014CN00180 申请日期 2014.02.26
申请人 ZHEJIANG YONGNING PHARMACEUTICAL CO LTD 发明人 YE, FENGQI;CAI, BEN;LU, MIN;CHEN, YONGLING
分类号 C07D309/10;A61K36/286;A61P7/02;A61P9/00;A61P9/10 主分类号 C07D309/10
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