A THERMODYNAMICALLY STABLE SOLID SOLUTION OF AGOMELATINE FOR USE IN A PHARMACEUTICAL FORMULATION

摘要

The invention provides a thermodynamically stable solid solution of agomelatine, containing agomelatine dissolved in a polymeric carrier, which is a copolymer of polyvinylpyrrolidone with polyvinyl acetate in the weight ratio of 3:2 (Kollidon VA64), its processes for preparing the same and pharmaceutical ' compositions containing agomelatine (N-[2-(7-methoxy-1-naphtyl)ethyl]-acetamide) of formula (I) and a process for the manufacture thereof.