摘要 |
The present invention relates to compounds of formula I in which n, R1, R2, R3a, R4 and R5 are defined in the Summary of the Invention; capable of inhibiting the activity of MEK. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of hyperproliferative diseases like cancer. |
申请人 |
NOVARTIS AG;BOCK, MARK GARY;MOEBITZ, HENRIK;PANIGRAHI, SUNIL KUMAR;PODDUTOORI, RAMULU;SAMAJDAR, SUSANTA |
发明人 |
BOCK, MARK GARY;MOEBITZ, HENRIK;PANIGRAHI, SUNIL KUMAR;PODDUTOORI, RAMULU;SAMAJDAR, SUSANTA |