| 发明名称 |
METHOD FOR CULTURING PLURIPOTENT STEM CELL, AND POLYPEPTIDE TO BE USED THEREFOR |
| 摘要 |
A polypeptide including: (1) a first region containing at least one selected from the group consisting of an amino acid sequence represented by CSYYQSC (SEQ ID NO:1) and an amino acid sequence represented by RGD; and (2) a second region containing (2-i) an amino acid sequence represented by PRPSLAKKQRFRHRNRKGYRSQRGHSRGRNQN (SEQ ID NO:2), (2-ii) an amino acid sequence having an identity of not less than 50% to the amino acid sequence represented by SEQ ID NO:2 and having an adsorption ability to a cultivation container, or (2-iii) an amino acid sequence that is the amino acid sequence represented by SEQ ID NO:2 in which from 1 to 30 amino acid residues are added, substituted, or deleted, and has an adsorption ability to a cultivation container, in which the polypeptide includes from 40 to 450 amino acid residues. |
| 申请公布号 |
US2015050737(A1) |
申请公布日期 |
2015.02.19 |
| 申请号 |
US201414528197 |
申请日期 |
2014.10.30 |
| 申请人 |
FUJIFILM CORPORATION |
发明人 |
MURAKAMI Yuta;IWATA Rie;IWAKI Yoshihide;SASAKI Tasuku |
| 分类号 |
C12N5/074;C07K14/00 |
主分类号 |
C12N5/074 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A polypeptide consisting of from 40 to 450 amino acid residues and comprising:
(1) a first region comprising at least one selected from the group consisting of an amino acid sequence represented by CSYYQSC (SEQ ID NO:1) and an amino acid sequence represented by RGD; and (2) a second region comprising
(2-i) an amino acid sequence represented by PRPSLAKKQRFRHRNRKGYRSQRGHSRGRNQN (SEQ ID NO:2),(2-ii) an amino acid sequence having an identity of not less than 50% to an amino acid sequence represented by SEQ ID NO:2 and having an adsorption ability to a cultivation container, or(2-iii) an amino acid sequence that is the amino acid sequence represented by SEQ ID NO:2, in which from 1 to 30 amino acid residues are added, substituted, or deleted, and that has an adsorption ability to a cultivation container. |
| 地址 |
Tokyo JP |
