发明名称 |
Verfahren zur Herstellung von 1,4-Dihydro-4-(2-trifluormethylphenyl)-pyridinen |
摘要 |
<p>(A) Pharmaceutical prepns. contng. as active ingredient a dihydropyridine deriv. (I) R' = 1-6C alkyl R2 = COOR', COR" R3 = Ph opt. substd. by mono/di-halo, mono/di/tri-1-4C alkyl/alkoxy, CF3; benzyl styryl, furyl, thienyl R4 = H, 1-6C alkyl R',R" = 1-6C alkyl (B) Cpds. of formula (II):- As hypotensive agents. Unit doses; 25-250 mg. for oral admin. at levels of 0.5-5 mg/kg.</p> |
申请公布号 |
CH498113(A) |
申请公布日期 |
1970.10.31 |
申请号 |
CH19680001693 |
申请日期 |
1968.02.06 |
申请人 |
SMITH KLINE & FRENCH LABORATORIES |
发明人 |
LOEV,BERNARD;EARL TEDESCHI,RALPH |
分类号 |
C07D211/02;C07D211/90;C07D213/80;C07D401/04;C07D405/04;C07D409/04;(IPC1-7):C07D29/40 |
主分类号 |
C07D211/02 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|