The present disclosure relates to an oral, immediate release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a carrier matrix used to deter abuse. The pill is prepared using hot melt extrusion and a forming unit through a continuous process. The formed pill is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.
申请公布号
WO2015023675(A2)
申请公布日期
2015.02.19
申请号
WO2014US50737
申请日期
2014.08.12
申请人
PHARMACEUTICAL MANUFACTURING RESEARCH SERVICES, INC.
发明人
THOMPSON, EDWIN, R.;THOMPSON, ERIC, R.;MYSLINSKI, NICHOLAS, R.;KEMENY, STEVEN, F.