| 发明名称 |
ANTI-SIGMAS FOR PROGRAMMABLE TRANSCRIPTIONAL REGULATION |
| 摘要 |
The invention relates to anti-sigma factors (“anti-sigmas”) that bind to sigma factors and block activation of transcription. Anti-sigmas and their cognate sigma factors provide a highly effective mechanism for regulating gene expression in genetic circuits. |
| 申请公布号 |
US2015051112(A1) |
申请公布日期 |
2015.02.19 |
| 申请号 |
US201314388030 |
申请日期 |
2013.03.15 |
| 申请人 |
Massachusetts Institute of Technology ;The Regents of the University of California |
发明人 |
Rhodius Virgil A.;Voigt Christopher;Gross Carol A. |
| 分类号 |
C40B30/02;C12N15/63 |
主分类号 |
C40B30/02 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A recombinant genetic circuit comprising:
an extracytoplasmic function (ECF) sigma factor; an anti-sigma factor that binds to the ECF sigma factor; and a promoter that is recognized by the ECF sigma factor. |
| 地址 |
Cambridge MA US |
