发明名称 |
Technology for the Preparation of Microparticles |
摘要 |
Microspheres are produced by contacting a solution of a macromolecule or small molecule in a solvent with an antisolvent and a counterion, and chilling the solution. The microspheres are useful for preparing pharmaceuticals, nutraceuticals, cosmetic products and the like of defined dimensions. |
申请公布号 |
US2015050713(A1) |
申请公布日期 |
2015.02.19 |
申请号 |
US201414341502 |
申请日期 |
2014.07.25 |
申请人 |
Ansun Biopharma, Inc. |
发明人 |
Malakhov Michael P.;Fang Fang |
分类号 |
C12N9/96;C12N7/00;C12N15/113;C07D305/14;C07K14/765;C07K9/00 |
主分类号 |
C12N9/96 |
代理机构 |
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代理人 |
|
主权项 |
1. A method of making microparticles of a compound, comprising:
a) adding a counterion to a solution containing the compound in a solvent; b) adding an antisolvent to the solution; and c) gradually cooling the solution to a temperature below about 25° C., whereby a composition containing microparticles comprising the compound is formed, wherein steps a), b) and c) are performed simultaneously, sequentially, intermittently, or in any order. |
地址 |
San Diego CA US |