主权项 |
1. A method of treating or preventing a disease selected from the group consisting of obesity, fatty liver, metabolic syndrome, insulin resistance syndrome, cardiovascular disease, hypertension and hyperlipidemia, comprising
step A: taking a predetermined amount of an extract from a peel of citrus fruit; step B: dissolving the extract with alcohols and then adding hydrochloric acid to obtain a first mixture; step C: incubating the first mixture with heating circumfluence, and then removing the alcohols, so as to obtain a second mixture; step D: extracting the second mixture by water and an organic solvent; step E: collecting an organic phase obtained with the organic solvent, and then purifying, so as to obtain a hydroxyl polymethoxylflavones (HPMFs) compound; and step F: administering an effective amount of a composition to a subject, the composition including the hydroxyl polymethoxylflavones compound, a pharmaceutically acceptable salt thereof, or a mixture thereof. |