发明名称 |
MICRORNA COMPOUNDS AND METHODS FOR MODULATING MIR-122 |
摘要 |
Described herein are compositions and methods for the inhibition of miR-122 activity. The compositions have certain nucleoside modifications that yield potent inhibitors of miR-122 activity. The compounds may comprise conjugates to facilitate delivery to the liver. The compositions may be administered to subjects infected with hepatitis C virus, as a treatment for hepatitis C virus and related conditions. |
申请公布号 |
WO2014179446(A3) |
申请公布日期 |
2015.02.19 |
申请号 |
WO2014US36137 |
申请日期 |
2014.04.30 |
申请人 |
REGULUS THERAPEUTICS INC. |
发明人 |
BHAT, BALKRISHEN;HOGAN, DANIEL |
分类号 |
C12N15/11;A61K31/7125;C12N15/113 |
主分类号 |
C12N15/11 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|