发明名称 |
AMIDE COMPOUND, PREPARATION METHOD AND USES THEREOF |
摘要 |
<p>Disclosed are amide compounds, preparation method and uses thereof, specifically, the compounds represented by formula I or pharmaceutically acceptable salts, wherein R 1 , R 2 , R 3 , R 4 , R 5 , Q, X and n are defined as in the description. Also disclosed are a method for preparing the compounds of formula I, a composition containing the compounds, and the uses of the same in the preparation of medicaments for regulating blood lipid and/or preventing gallstone. The compounds of formula I disclosed in the present invention have stability in vitro, good solubility in the pharmaceutical organic solvents and favorable bioavailability in animals.</p> |
申请公布号 |
EP2725010(A4) |
申请公布日期 |
2015.02.18 |
申请号 |
EP20120802606 |
申请日期 |
2012.06.25 |
申请人 |
SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY;CHINA STATE INSTITUTE OF PHARMACEUTICAL INDUSTRY |
发明人 |
YU, ZHENPENG;WANG, GUOPING;ZHANG, ZHEN;LIU, MINYU;HUANG, XIAOLING;LIU, YING;XIAO, LIN;CAI, LI;WU, XUEJUN;DENG, YIFANG;PAN, MIANLI;CHEN, RENHAI;TANG, SHENRONG;LIU, QUANHAI |
分类号 |
C07C235/20;A61K31/165;A61K31/166;A61K31/222;A61P1/16;C07C231/02 |
主分类号 |
C07C235/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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