METHOD AND DEVICE FOR RAPID DNP

摘要

A method for producing hyperpolarized sample material for use in magnetic resonance investigations involves preparing a target material containing high gamma nuclei with a short T1, a polarizing agent with a broad EPR line, and low gamma nuclei with a long T1. The polarizing agent in the target material is irradiated with microwave radiation, wherein the target material is at a cryogenic temperature and exposed to a static magnetic field B0>=4.0 T, thus polarizing the high gamma nuclei by DNP, and the polarization is transferred from the high gamma nuclei to the low gamma nuclei by Cross Polarization. A dissolved sample material is prepared containing the hyperpolarized low gamma nuclei from the target material. Nuclei with a long longitudinal relaxation time T1 can thereby be quickly hyperpolarized to a high polarization level.