| 发明名称 |
METHOD FOR ENANTIOSELECTIVE HYDROGENATION OF CHROMENES |
| 摘要 |
<p>A method for preparing an enantiomeric chromane, by asymmetrically hydrogenating a chromene compound in the presence of an Ir catalyst having a chiral ligand. The method includes the enantioselective preparation of enantiomeric equol. A preferred Ir catalyst has a chiral phosphineoxazoline ligand. Enantiomeric chromanes of high stereoselective purity can be obtained.</p> |
| 申请公布号 |
EP1919887(B1) |
申请公布日期 |
2015.02.18 |
| 申请号 |
EP20060788891 |
申请日期 |
2006.08.01 |
| 申请人 |
GIRINDUS AMERICA, INC.;CHILDREN'S HOSPITAL MEDICAL CENTER |
发明人 |
SETCHELL, KENNETH DAVID REGINALD;SOROKIN, VICTOR, DMITRIEVICH |
| 分类号 |
C07D311/02;C07D231/02;C07D311/04;C07F15/00 |
主分类号 |
C07D311/02 |
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