发明名称 ARIL-ÉTER PIRROLIDINA COMO ANTAGONISTAS DO RECEPTOR NK3
摘要 <p>The invention relates to a compound of formula I wherein Ar1, Ar2, R1, R2, R3, R4, n, o, p, and q are as defined herein and to a pharmaceutically active salt thereof, including all stereoisomeric forms, individual diastereoisomers and enantiomers of the compound of formula (I) as well as racemic and non-racemic mixtures thereof. The compounds are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).</p>
申请公布号 BRPI0815658(A2) 申请公布日期 2015.02.18
申请号 BR2008PI15658 申请日期 2008.07.29
申请人 F. HOFFMANN-LA ROCHE AG 发明人 PHILIPPE JABLONSKI;KENICHI KAWASAKI;HENNER KNUST;ANJA LIMBERG;MATTHIAS NETTKOVEN;HASANE RATNI;CLAUS RIEMER;XIHAN WU
分类号 C07D401/08;C07D401/06 主分类号 C07D401/08
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