| 发明名称 |
ARYL TRIAZOLE COMPOUNDS WITH ANTITUMOURAL ACTIVITY |
| 摘要 |
The present invention relates to aryl triazole derivatives of Formula I having antitumoural activity through, as one possible biological target, the molecular chaperone heat shock protein 90 (Hsp90) inhibition. The invention includes the use of such compounds in medicine, in relation to cancer disease as well as other diseases where an inhibition of Hsp90 is responsive, and the pharmaceutical composition containing such compounds. |
| 申请公布号 |
EP2655345(B1) |
申请公布日期 |
2015.02.18 |
| 申请号 |
EP20110805449 |
申请日期 |
2011.12.13 |
| 申请人 |
SIGMA-TAU RESEARCH SWITZERLAND S.A. |
发明人 |
GIANNINI, GIUSEPPE;CABRI, WALTER;VESCI, LOREDANA;CERVONI, MARIA LUISA;PISANO, CLAUDIO;TADDEI, MAURIZIO;FERRINI, SERENA |
| 分类号 |
C07D249/06;A61K31/4192;A61P35/00;C07D413/12 |
主分类号 |
C07D249/06 |
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