发明名称 |
Dipeptoid prodrugs and their use |
摘要 |
The present application relates to prodrug derivatives of 2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-4-[4-(2-hydroxyethoxy)phenyl]pyridine-3,5-dicarbonitrile, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of cardiovascular disorders. |
申请公布号 |
US8957017(B2) |
申请公布日期 |
2015.02.17 |
申请号 |
US201414219872 |
申请日期 |
2014.03.19 |
申请人 |
Bayer Intellectual Property GmbH |
发明人 |
Lerchen Hans-Georg;Krenz Ursula;Keldenich Jörg;Diedrichs Nicole;Krahn Thomas;Hirth-Dietrich Claudia;Albrecht-Küpper Barbara |
分类号 |
A61K38/00;A61K47/00;C07K5/068;C07D417/12 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
King Karen B. |
主权项 |
1. A compound having the formula |
地址 |
Monheim DE |