| 发明名称 | Method of making composite particles for use in pharmaceutical compositions and composite particles and compositions thereof | ||
| 摘要 | The invention relates to a method for making composite active particles for use in a pharmaceutical composition for pulmonary administration, the method comprising a milling step in which particles of active material are milled in the presence of particles of an additive material which is suitable for the promotion of the dispersal of the composite active particles upon actuation of an inhaler. The invention also relates to compositions for inhalation prepared by the method. | ||
| 申请公布号 | US8956661(B2) | 申请公布日期 | 2015.02.17 |
| 申请号 | US201213623326 | 申请日期 | 2012.09.20 |
| 申请人 | Vectura Limited | 发明人 | Staniforth John Nicholas;Green Matthew Michael James;Morton David Alexander Vodden |
| 分类号 | A61K9/16;A61K9/50;A61K9/00;A61K9/14 | 主分类号 | A61K9/16 |
| 代理机构 | Reed Smith LLP | 代理人 | Hank Maryellen Feehery;Reed Smith LLP |
| 主权项 | 1. A method for making composite active particles for use in a pharmaceutical composition for pulmonary administration, the method comprising a milling step in which particles of active material are milled in the presence of particles of an additive material which is suitable for the promotion of the dispersal of the composite active particles upon actuation of an inhaler wherein the mass median aerodynamic diameter of the composite active particles is not more than 10 μm after milling. | ||
| 地址 | Chippenham, Wiltshire GB | ||