Medical device applications of nanostructured surfaces

摘要

This invention provides novel nanofiber enhanced surface area substrates and structures comprising such substrates for use in various medical devices, as well as methods and uses for such substrates and medical devices. In one particular embodiment, methods for enhancing cellular functions on a surface of a medical device implant are disclosed which generally comprise providing a medical device implant comprising a plurality of nanofibers (e.g., nanowires) thereon and exposing the medical device implant to cells such as osteoblasts.

主权项

1. A wound dressing comprising:
a plurality of nanostructures; and a bandage that includes a fibrous web, wherein at least a portion of the plurality of nanostructures are incorporated within or associated with the fibrous web; wherein at least a portion of the plurality of nanostructures are bent, curved, curled, or coiled; and wherein a surface of the bandage is capable of adhering to a biological tissue surface due at least to van der Waals forces between at least a portion of the plurality of nanostructures and the biological tissue surface.