发明名称 |
Concentrate of omega 3 |
摘要 |
An efficient and simple process to obtain a concentrate that includes over 80% in weight of ethyl esters of ω-3 fatty acids based on a composition of matter that contains esters of ω-3 fatty acids or free ω-3 fatty acids that comprises the stages of:
a) contacting the composition of matter with ethanol of at least 96% in weight and a hydroxide of an alkali metal at a temperature between 60 and 200° C. to form a liquid mixture that includes alkaline salts of fatty acids;b) cool the liquid mixture to a temperature between 50 and −20° C. to form a solid phase and a liquid phase and separate the liquid phase from the solid phase;c) contact the separated liquid phase of stage b) with an acid to form an acidified mixture with a water content under 10%, where the mixture consists of a solid phase that includes the alkali metal salt of the acid and a liquid phase that comprises ω-3 fatty acids;d) heat the mixture of stage c) between 50 to 150° C. in the presence of an esterification catalyst to form a mixture that includes ethyl esters of ω-3 fatty acids;e) contact the mixture of stage d) with an alkali to form a neutralized mixture;f) distill the neutralized mixture to obtain a distillate that includes over 80% in weight of ethyl esters of ω-3 fatty acids. |
申请公布号 |
US8957231(B2) |
申请公布日期 |
2015.02.17 |
申请号 |
US201113994785 |
申请日期 |
2011.12.25 |
申请人 |
Golden Omega S.A. |
发明人 |
Sepulveda Reyes Juvenal Antonio;Berrios Cornejo Miriam Rosa;Fuenzalida Dias Miguel Angel;Markovits Rojas Alejandro;Harting Glade Thomas Francis |
分类号 |
C07C51/00;C11B3/00;A23D9/00;C11B1/10;C11C1/10;C11C3/00;C11C1/08 |
主分类号 |
C07C51/00 |
代理机构 |
Fish & Richardson P.C. |
代理人 |
Fish & Richardson P.C. |
主权项 |
1. A process for obtaining a concentrate containing more than 80% by weight of ethyl esters of ω-3 fatty acids based on a composition of matter that contains esters of ω-3 fatty acids or free ω-3 fatty acids, which comprises:
a) contacting the composition of matter with ethanol of at least 96% in weight and a hydroxide of an alkaline metal at a temperature between 60 and 200° C. to form a liquid mixture that includes alkaline salts of fatty acids; b) cooling the liquid mixture to a temperature between 50 and −20° C. to form a solid phase and a liquid phase and separating the liquid phase from the solid phase; c) contacting the separated liquid phase of stage b) with an acid to form an acidified mixture with a water content under 10%, wherein the mixture consists of a solid phase that includes the alkali metal salt of the acid and a liquid phase that comprises ω-3 fatty acids; d) heating the mixture of stage c) to between 50 and 150° C. in the presence of an esterification catalyst to form a mixture that includes ethyl esters of ω-3 fatty acids; e) contacting the mixture of stage d) with an alkali to form a neutralized mixture; and f) distilling the neutralized mixture to obtain a distillate that contains in excess of 80% by weight of ethyl esters of ω-3 fatty acids. |
地址 |
Santiago CL |