发明名称 |
Agents from cells |
摘要 |
A composition includes an isolated cell; at least one particle within said cell; and at least one active agent associated with the particle, wherein the active agent is capable of being released from the cell. A method includes administration of such a cell to a subject. |
申请公布号 |
US8956863(B2) |
申请公布日期 |
2015.02.17 |
申请号 |
US201013501475 |
申请日期 |
2010.10.15 |
申请人 |
The Brigham and Women's Hospital, Inc. |
发明人 |
Karp Jeffrey M.;Sarkar Debanjan;Vemula Praveen Kumar |
分类号 |
C12N5/00;C12N5/02;C12N15/63;A61K47/48;A61K38/18 |
主分类号 |
C12N5/00 |
代理机构 |
Fish & Richardson P.C. |
代理人 |
Fish & Richardson P.C. |
主权项 |
1. A composition comprising:
a) an isolated mammalian cell; b) at least one particle comprising a polymer and having a size of about 1 μm to 2 μm within the cell; and c) at least one active agent associated with the particle; wherein the active agent is capable of being released from inside the cell independently of the particle. |
地址 |
Boston MA US |