发明名称 PROCESS FOR THE PREPARATION OF N-[5-(3,5-DIFLUORO-BENZYL)-1H-INDA ZOL-3-YL]-4-(4-METHYL-PIPERAZIN-1-YL)-2-(TETRAHYDRO-PYRAN-4-YLAM INO)-BENZAMIDE.
摘要 The present invention relates to a process for the preparation of N-[5-(3,5-difluoro-benzyl)-1H-indazol-3-yl]-4-(4-methyl- piperazin-1-yl)-2-(tetrahydro-pyran-4-ylamino)-benzamide. Novel solid forms of this compound, their utility in treating diseases caused by deregulated protein kinase activity and pharmaceutical compositions containing them are also object of the present invention.
申请公布号 MX2014013924(A) 申请公布日期 2015.02.17
申请号 MX20140013924 申请日期 2013.05.22
申请人 NERVIANO MEDICAL SCIENCES S.R.L. 发明人 NATALE ALVARO BARBUGIAN;ROMUALDO FORINO;TIZIANO FUMAGALLI;PAOLO ORSINI
分类号 C07D405/12;A61K31/496;A61P35/00 主分类号 C07D405/12
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