摘要 |
一种细胞植入用之基质,该基质具有大于80%之连接孔隙度并主要由可生物吸收之复数聚合物的混合物所构成,其中该基质为碟形且其中该碟之一侧上之表面层的平均孔隙密度小于其他侧之平均孔隙密度的20%。;该基质系由下列方法所制造:提供可生物吸收之聚合物层;在该聚合物层上单侧地使一水溶性固体、具有不同再吸收速率之至少两种聚合物、及此等聚合物中之一者用之溶剂的一混合物形成膜层;蒸发该溶剂并选择性地接着压实该混合物;及对该结实体浇水以移除该盐。;The matrix is manufactured by providing a bioresorbable polymer layer; stratifying, onto the polymer layer, a mixture of a water-soluble solid, at least two polymers differing with respect to their resorption rates, and a solvent for one of the polymers; evaporating the solvent optionally followed by compacting the mixture; and watering the compacted body to remove the salt. |