Expression vector comprising gene coding prion protein from Capra aegagrus hircus and transfected cell by the same

摘要

The present invention relates to an expression vector comprising a gene encoding a prion protein of Capra hircus and a cell transduced by the vector. The present invention can be used for manufacturing a cell having polymorphism, which represents Capra hircus bred in Korea, and a transduced mouse; and can be effectively used for developing an animal experimental model for studies including diagnosis of prion diseases which include scrapie occurred in goat family animals, and for confirming if domestic TSE diseases interspecifically spread or not.