Proteínas de fusión que comprenden una molécula de inmunoglobulina y dos moléculas de interleuquina-2 (il-2); polinucleótido que la codifica; vector; célula huésped; método de producción; composición farmacéutica; y uso para tratar una enfermedad autoinmunológica.

摘要

The present invention generally relates to fusion proteins of immunoglobulins and interleukin-2 (IL-2). In addition, the present invention relates to polynucleotides encoding such fusion proteins, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the fusion proteins of the invention, and to methods of using them in the treatment of disease.