Endometrial Phase or Endometrial Cancer Biomarkers

摘要

Methods for detecting endometrial diseases or an endometrium phase in a subject are described comprising measuring endometrial markers or polynucleotides encoding the markers in a sample from the subject. The invention also provides localization or imaging methods for endometrial diseases, and kits for carrying out the methods of the invention. The invention also contemplates therapeutic applications for endometrial diseases employing endometrial markers, polynucleotides encoding the markers, and/or binding agents for the markers.

主权项

1: A method for diagnosing an endometrial disease or an endometrial phase in a mammalian subject by detecting one or more endometrial markers, or polynucleotides encoding the one or more endometrial markers, associated with an endometrial disease, the method comprising:
(a) measuring in a biological sample obtained from the subject an amount of one or more endometrial markers of Table 1, or polynucleotides encoding the one or more markers; and (b) comparing the measured amount of one or more endometrial markers or polynucleotides encoding the one or more markers with a standard amount, wherein a difference between the detected amount and the standard amount is indicative of the presence of endometrial disease or of the endometrium phase.