SIRT1 INHIBITORS AND STEM CELL REJUVENATION

摘要

Provided herein are, inter alia, methods and compositions for treating or preventing diseases using SIRT1 inhibitors. The methods provided herein are particularly useful for treating or preventing age-related hematological diseases as well as cancerous hematological diseases. Further provided herein are hematopoietic cells useful for treating or preventing hematological diseases.

主权项

1. A method of treating or preventing a hematological disease in a subject in need thereof, said method comprising administering a therapeutically effective amount of a SIRT1 inhibitor to a subject, thereby treating or preventing a hematological disease in said subject, wherein said disease is not a cancerous hematological disease.