| 摘要 |
A catheterization system for treatment of a condition within a blood vessel is provided with a catheter, a balloon immediately adjacent to the distal end of the catheter, an inflation device for expanding the balloon, and a fluid injection device for injecting a treatment fluid through the central lumen of the catheter and out of the aperture at the distal end of the catheter into the treatment area. The system may include an RF wire, a hollow needle wire, a dissection tool, or a laser wire insertable through the central lumen of the catheter and selectively operable adjacent the proximal end of the catheter to apply treatment within the blood vessel. |
| 主权项 |
1. A catheterization system for treatment of a condition within a blood vessel, the system comprising:
a support catheter defining a proximal end, a distal end, a central lumen interconnecting the ends, and an aperture at the distal end, the catheter insertable into the blood vessel to a treatment area that is substantially distal of the distal end of the catheter, wherein the central lumen is configured to permit the advancement of a wire therethrough to the treatment area; a flexible membrane mounted on an outside surface of the catheter and disposed immediately adjacent to the aperture at the distal end of the catheter while deflated, the flexible membrane including a proximal end and an opposite distal end, wherein the distal end of the catheter projects slightly beyond the distal end of the flexible membrane when the flexible membrane is fully inflated; wherein the flexible membrane, when inflated, has a substantially cylindrical shape and is positioned to minimize contact between the vessel and a treatment fluid and/or debris; an inflation device selectively operable adjacent the proximal end of the catheter and coupled to the flexible membrane to be capable of expanding the membrane under pressure to create an atraumatic seal with a vessel wall and substantially close off the blood vessel; and a fluid injection device selectively operable adjacent the proximal end of the catheter to inject a treatment fluid through the central lumen of the catheter and out of the aperture at the distal end of the catheter into the treatment area, wherein the treatment fluid is a tissue-killing fluid. |
