| 发明名称 |
THIENO[2,3-C]PYRANS AS CFTR MODULATORS |
| 摘要 |
The present invention discloses compounds according to Formula I: Wherein R is as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment cystic fibrosis by administering a compound of the invention. |
| 申请公布号 |
WO2015018823(A1) |
申请公布日期 |
2015.02.12 |
| 申请号 |
WO2014EP66806 |
申请日期 |
2014.08.05 |
| 申请人 |
GALAPAGOS NV |
发明人 |
VAN DER PLAS, STEVEN EMIEL;MARTINA, SÉBASTIEN LAURENT XAVIER;DROPSIT-MONTOVERT, SÉBASTIEN JEAN-JACQUES CÉDRIC;ANDREWS, MARTIN JAMES INGLIS;KELGTERMANS, HANS |
| 分类号 |
C07D495/04;A61K31/38 |
主分类号 |
C07D495/04 |
| 代理机构 |
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