| 发明名称 |
Salts of a dihydroquinazoline derivative |
| 摘要 |
The invention relates to besylate and tosylate salts of {8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4-yl}acetic acid and solvates thereof, to the use thereof in a method of treating and/or preventing virus infections, and to the use thereof to produce drugs for use in treating and/or preventing diseases, in particular use as antiviral agents, in particular against cytomegaloviruses. |
| 申请公布号 |
US2015045371(A1) |
申请公布日期 |
2015.02.12 |
| 申请号 |
US201314381625 |
申请日期 |
2013.02.28 |
| 申请人 |
AiCuris GmbH & Co. KG |
发明人 |
Maertens Welljanne;Schickaneder Christian |
| 分类号 |
C07D239/84;C07C309/30;C07C309/29 |
主分类号 |
C07D239/84 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A salt of {8-fluoro-2-[4-(3-methoxyphenyl)piperazine-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazoline-4-yl}acetic acid or a solvate thereof selected from the group consisting of the crystalline besylate salts of {8-fluoro-2-[4-(3-methoxyphenyl)piperazine-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquhinazoline-4-yl}acetic acid, the crystalline tosylate salts of {8-fluoro-2-[4-(3-methoxyphenyl)piperazine-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazoline-4-yl}acetic acid and solvates thereof. |
| 地址 |
Wuppertal DE |
