发明名称 |
Sistema de suministro de polímero estabilizado |
摘要 |
<p>The invention relates to a delivery system for the sustained and controlled delivery of a group of bioactive agents. More particularly, the invention relates to a delivery system and a method for delivery of a bioactive agent containing a nucleophilic functional group by means of a biodegradable, sustained-release implant. The implant may be a preformed implant, microparticles or an in situ formed implant. The implant includes a biodegradable thermoplastic polymer, the bioactive agent having a nucleophilic group substituent and a stabilizing associate as well as other optional components. The combination of the stabilizing associate with the bioactive agent prevents and/or minimizes and/or lessens degradation of the thermoplastic polymer by the bioactive agent.</p> |
申请公布号 |
ES2528720(T3) |
申请公布日期 |
2015.02.12 |
申请号 |
ES20050819495T |
申请日期 |
2005.11.10 |
申请人 |
TOLMAR THERAPEUTICS, INC. |
发明人 |
ZHOU, MINGXING;DADEY, ERIC |
分类号 |
A61K9/50;A61K9/00;A61K9/52;A61K9/62;A61K9/64;A61K47/02;A61K47/12;A61K47/34;A61L27/18;A61L27/58 |
主分类号 |
A61K9/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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