PHOTOACOUSTIC IMAGING AGENT WHICH HAS LIPID PARTICLE CONTAINING SILICON NAPHTHALOCYANINE ANALOG

摘要

PROBLEM TO BE SOLVED: To solve a problem that a conventional liposome containing silicon naphthalocyanine should be encapsulated in condition where dyes are dispersing, to be used in photodynamic therapy; is low in dye-containing rate; and also is low in a photoacoustic signal.SOLUTION: According to a lipid particle containing silicon naphthalocyanine analog, wherein ratio A/B of absorption coefficient A in first absorption maximum and absorption coefficient B in second absorption maximum in 700 nm to 800 nm is 5.0 or less, it is possible that the dye-containing rate in the lipid particle is increased and thereby intensity of a photoacoustic signal is improved.