摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a knockout nonhuman animal or the like, usable for screening a remedy for arteriosclerosis. <P>SOLUTION: There is provided the knockout nonhuman animal or a part thereof from which functions of the whole or a part of LDLR gene, and the whole or a part of at least one gene selected from the group consisting of EBI3 gene, IL27-p28 gene and WSX-1 gene are deleted. <P>COPYRIGHT: (C)2011,JPO&INPIT</p> |