发明名称 |
COMBINATION OF A 6-OXO-1,6-DIHYDRO-PYRIDAZINE DERIVATIVE HAVING ANTI-CANCER ACTIVITY WITH OTHER ANTI-TUMOR COMPOUNDS |
摘要 |
A pharmaceutical composition of 3-(1-{3-[5-(1-Methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile or a pharmaceutically acceptable salt and/or solvate thereof in combination with a compound selected from the group erlotinib, cetuximab, aflibercept, bevacizumab. |
申请公布号 |
US2015044211(A1) |
申请公布日期 |
2015.02.12 |
申请号 |
US201314386164 |
申请日期 |
2013.02.21 |
申请人 |
MERCK PATENT GMBH |
发明人 |
Bladt Friedhelm;Friese-Hamim Manja |
分类号 |
A61K31/506;A61K31/517;A61K39/395 |
主分类号 |
A61K31/506 |
代理机构 |
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代理人 |
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主权项 |
1. A pharmaceutical composition of 3-(1-{3-[5-(1-Methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile or a pharmaceutically acceptable salt and/or solvate thereof in combination with a compound selected from the group erlotinib, cetuximab, aflibercept, bevacizumab. |
地址 |
Darmstadt DE |