The present invention provides, methods end composites for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with neurofibrillary tangles. In particular, the Invention relates to humanized antibodies, which specifically recognize and bind to phosphorylated pathological protein tau-conformers to methods and compositions involving antibodies for the therapeutic and diagnostic use In the treatment of tauopathies including Alzheimer's Disease (AD).
申请公布号
EP2834270(A1)
申请公布日期
2015.02.11
申请号
EP20130714429
申请日期
2013.03.15
申请人
AC IMMUNE S.A.;KATHOLIEKE UNIVERSITEIT LEUVEN;GENENTECH, INC.