发明名称 METHOD FOR PRODUCING MIDDLE-CHAIN OMEGA-HYDROXY FATTY ACIDS, ALPHA AND OMEGA-DICARBOXYLIC ACIDS, AND OMEGA-AMINO FATTY ACIDS FROM LONG-CHAIN FATTY ACIDS BY BIOTRANSFORMATION
摘要 The present invention relates to a transformant which is transformed to express Baeyer-Villiger monooxygenase (BVMO), a method for producing C5-C14 medium-chain É-hydroxy fatty acids, ±,É-dicarboxylic acids, É-amino fatty acids, or alcohols from C16-C20 long-chain fatty acids by biotransformation using the transformant, a method for producing a fatty acid derivative having an ester group which is introduced into the chain thereof from keto fatty acid using the BVMO, and novel É-hydroxy fatty acids which are prepared by the method. Degradation products such as C5 to C14 É-hydroxy fatty acids, ±,É-dicarboxylic acids, É-amino fatty acids, alcohols can be produced in a large amount from C16 to C20 long-chain fatty acids contained in a medium by biotransformation using a transformant capable of expressing BVMO of the present invention. Therefore, it can be widely used to produce É-hydroxy fatty acids, ±,É-dicarboxylic acids, É-amino fatty acids or alcohols in a more safe and economic manner.
申请公布号 EP2835425(A1) 申请公布日期 2015.02.11
申请号 EP20130771758 申请日期 2013.04.05
申请人 EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION 发明人 PARK, JIN BYUNG;SONG, JI WON;JEON, EUN YEONG
分类号 C12N15/53;C07C59/01;C12N1/21;C12N15/63;C12P7/06 主分类号 C12N15/53
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