发明名称 |
SUBUNIT VACCINE DELIVERY PLATFORM FOR ROBUST HUMORAL AND CELLULAR IMMUNE RESPONSES |
摘要 |
The present invention relates to a probiotic cell transformed with a construct suitable to overexpress and display on the surface of the probiotic cell a fusion protein comprising at least a portion of a transport protein coupled to at least a portion of one or more antigenic proteins or peptides. Probiotic-derived vesicles displaying this fusion protein as well as methods of inducing an immune response using the probiotic cells or vesicles are also disclosed. |
申请公布号 |
EP2833911(A2) |
申请公布日期 |
2015.02.11 |
申请号 |
EP20130772865 |
申请日期 |
2013.03.13 |
申请人 |
CORNELL UNIVERSITY |
发明人 |
PUTNAM, DAVID A.;ROSENTHAL, JOSEPH;HUANG, CHUNG-JR.;DELISA, MATTHEW;MENDEZ, SUSANA |
分类号 |
A61K39/08 |
主分类号 |
A61K39/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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