This disclosure concerns compounds which are useful as inhibitors of protein kinase C (PKC) and are thus useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of PKC. This disclosure also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
申请公布号
EP2833889(A1)
申请公布日期
2015.02.11
申请号
EP20130773141
申请日期
2013.04.04
申请人
RIGEL PHARMACEUTICALS, INC.
发明人
SINGH, RAJINDER;DUNCTON, MATTHEW;ZHANG, JING;ALVAREZ, SALVADOR;TSO, KIN;HOLLAND, SACHA;YEN, ROSE;KOLLURI, RAO;HECKRODT, THILO;CHEN, YAN;MASUDA, ESTEBAN;LI, HUI;PAYAN, DONALD G.;KELLEY, RYAN