Gelatin-transglutaminase hemostatic dressings and sealants

摘要

A composition comprising a combination of gelatin and transglutaminase, wherein a ratio of an amount of said gelatin and an amount of said transglutaminase is sufficient to reduce bleeding in a wound of a mammal, wherein said gelatin does not undergo thermoreversible gelation, and wherein said gelatin is produced from animal origin, recombinant origin or a combination thereof; and medical devices and dressings incorporating this composition.