Method for principal frequency magnetic resonance elastography inversion

摘要

A method for calculating a mechanical property of a material using a magnetic resonance imaging (“MRI”) system is provided. The method is particularly robust to image data having low signal-to-noise ratio (“SNR”). An MRI system is used to acquire magnetic resonance elastography (“MRE”) data from a subject containing the material. Exemplary materials include lung tissue. Images are reconstructed from the MRE data and used to produce a wave image from which a spatial frequency spectrum is produced. A principal frequency of the spatial frequency spectrum is produced and used to calculate a mechanical property of the material. For example, shear stiffness may be calculated.

主权项

1. A method for calculating a mechanical property of a material using a magnetic resonance imaging (MRI) system, the steps of the method comprising:
a) acquiring with the MRI system, magnetic resonance elastography (MRE) data from a subject containing the material; b) reconstructing images from the MRE data acquired in step a); c) producing a complex wave image from the images reconstructed in step b); d) producing a spatial frequency spectrum from the complex wave image produced in step c); e) calculating a principal frequency of the spatial frequency spectrum produced in step d); and f) calculating a mechanical property of the material using the complex wave image produced in step c) and the principal frequency calculated in step e).