| 发明名称 | Recombinant FSH including alpha 2,3- and alpha 2,6-sailylation | ||
| 摘要 | The present disclosure describes recombinant follicle stimulating hormone (FSH) and methods for the production thereof. The recombinant FSH can include α2,3, α2,6, and, optionally, α2,8 sialylation. The recombinant FSH can be produced in a human cell line such as a PER.C6® cell line. | ||
| 申请公布号 | US8951967(B2) | 申请公布日期 | 2015.02.10 |
| 申请号 | US200912988218 | 申请日期 | 2009.04.16 |
| 申请人 | Ferring International Center SA | 发明人 | Cottingham Ian;Plaksin Daniel;White Richard Boyd |
| 分类号 | A61K38/24;C07K14/59;A61P5/06;C12P21/00;A61K38/00 | 主分类号 | A61K38/24 |
| 代理机构 | Fish & Richardson P.C. | 代理人 | Fish & Richardson P.C. |
| 主权项 | 1. Recombinant FSH comprising α2,3- and α2,6-sialylation, wherein 60% or more of the total sialylation of the recombinant FSH is α2,3-sialylation and 5 to 20% of the total sialylation of the recombinant FSH is α2,6-sialylation. | ||
| 地址 | Saint-Prex CH | ||